This program provides an overview of the structure and functions of the kidneys and details about the major structural compartments of the kidney, including the renal vasculature, glomeruli, tubules, and interstitium. These compartments are discussed at the ultrastructural and molecular levels. Additional discussion includes the functions of these compartments and how they link to structure. Further, integrated functions of the kidneys that lead to the maintenance of body homeostasis are covered.
Course Objective(s)
Upon completion of the program, the participant will be able to:
1) explain the complex course that results in normal nephron and kidney development or congenital abnormalities of the kidneys and urinary tract
2) outline the components of the nephron and how they work in concert to form urine
3) discuss the varied roles of the kidney in homeostasis and how alterations can result in a range of disorders related to volume, electrolytes, or proteinuria
4) identify new research questions to build on current understanding of kidney physiology
Content :
On Demand
Presentations
Overview of Kidney Development
Norman D. Rosenblum, MD
Tubule Homeostasis
Lloyd G. Cantley, MD, FASN
Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
Indra R. Gupta, MD
Glomerular Structure and Function
David J. Salant, MBChB, MD
Abnormalities of Glomerular Structure
Astrid Weins, MD, PhD, FASN
Renal Vasculature and Hemodynamics
Heather A. Drummond, PhD
Control of Volume and Osmolality
Joseph G. Verbalis, MD
Endocrine Functions of the Kidneys
Mitchell H. Rosner, MD, FASN
Mechanisms of Hypertension and the Kidneys
Jordana B. Cohen, MD, MS, FASN
The Renal Interstitium
Dennis G. Moledina, MD, PhD, FASN
Defining Tubular Segments
Mark A. Knepper, MD, PhD
Proximal Tubule
Melanie P. Hoenig, MD
Thick Ascending Limb of the Loop of Henle
Jeff M. Sands, MD, FASN
Distal Convoluted Tubule
Ewout J. Hoorn, MD, PhD
Collecting Duct
Nuria M. Pastor-Soler, MD, PhD, FASN
Livestream
Presentations
Welcome and Introduction – Co-Chairs
01:30 PM EDT – 01:35 PM EDT
Emerging Technologies for Studying the Glomerular Filtration Barrier
01:35 PM EDT – 02:00 PM EDT
Sargis Sedrakyan, PhD
Urinary Single-Cell Profiling
02:00 PM EDT – 02:25 PM EDT
Katalin Susztak, MD, PhD
Extracellular Vesicles
02:25 PM EDT – 02:50 PM EDT
Uta Erdbruegger, MD
Panel Discussion and Q&A
02:50 PM EDT – 03:00 PM EDT